Scientific Name: Sus scrofa domestica
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Artiodactyla-> Suina-> Suidae-> Sus-> Sus scrofa
Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_0046 | 2021.04 | 10X Genomics | Lung | Normal | 21981 | Link |
Vthunter_0069 | 2021.04 | 10X Genomics | Frontal | Normal | 8812 | Link |
Vthunter_0070 | 2021.04 | 10X Genomics | Occipital | Normal | 6829 | Link |
Vthunter_0071 | 2021.04 | 10X Genomics | Parietal | Normal | 6162 | Link |
Vthunter_0072 | 2021.04 | 10X Genomics | Hypothalamus | Normal | 7302 | Link |
Vthunter_0073 | 2021.04 | 10X Genomics | Temporal | Normal | 3145 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_0074 | 2021.04 | iDrop | Lung | Normal | 13580 | Link |
Vthunter_1013 | 2019.12 | 10X Genomics | Lung | Normal | 7465 | Link |
Vthunter_1014 | 2019.12 | 10X Genomics | Lung | Normal | 3987 | Link |
Featureplot of receptors
Expression: Broad expression in appendix (RPKM 16.6), lymph node (RPKM 11.0) and 16 other tissues?